Healthcare AI startup Abridge has secured $300 million in Series E funding led by Andreessen Horowitz, with participation from Khosla Ventures, to revolutionize clinical documentation and revenue cycle management.

The Pittsburgh-based company addresses a critical pain point in healthcare: the $1.5 trillion annual administrative burden that contributes to physician burnout. Abridge's AI platform converts medical conversations into compliant documentation in real-time, eliminating the need for manual coordination between clinicians and billing teams.

The platform has achieved impressive scale, serving over 150 enterprise health systems across 55 medical specialties and 28 languages. This year alone, Abridge will process more than 50 million medical conversations, with studies showing it reduces clinician burnout by 60-70% and maintains a 90% user retention rate.

What sets Abridge apart is its approach—embedding revenue cycle intelligence directly into clinical conversations rather than as an afterthought. The platform captures billing codes, risk adjustment data, and compliance requirements, enabling doctors to focus on patient care and revenue cycle management (RCM) teams to become more efficient in their operations.

CEO Dr. Shiv Rao emphasized the company's mission: "Every medical conversation is rich with signals our healthcare system depends on. Abridge activates those signals in the background, silently handling complexity so clinicians can focus on human moments that matter."